Nursing Informatics RN to MSN Programs

Are you a working nurse looking to advance in IT leadership? Learn everything you need to know about RN to MSN Nursing Informatics degrees. Explore 100% online program options, get a rundown on key nursing informatics certifications like the NI-BC credential, and find links to top informatics conferences, professional organizations, and career resources. Don’t miss the section on job opportunities and salary insights in this rapidly growing field!

Already a convert? Skip ahead to our Directory of RN to MSN Nursing Informatics Programs.

What is Nursing Informatics?

Definition of Nursing Informatics

Nursing informatics is a specialty field that integrates clinical knowledge & nursing science with information science & communication technologies to improve the health of patients, families, and communities.

In practical terms, this means nursing informatics specialists are responsible for dealing with all kinds of healthcare information technologies & processes, including:

• Electronic Health Records (EHR) systems
• Implementation training & consulting
• Healthcare system design & development
• Ensuring data security & privacy
• Overseeing data infrastructures
• Information retrieval & presentation
• Process improvement & workflow (e.g. expediting patient test results)
• Data analysis (e.g. evaluating staffing needs)
• Actionable data science projects (e.g. improving patient safety)

Well-trained graduates work for:

• Hospitals & healthcare systems in mid-level and high-level positions (e.g. Chief Information Officer)
• Healthcare software companies, IT vendors, and analytics businesses
• IT consulting firms
• Federal agencies (e.g. Centers for Medicare and Medicaid Services)
• Public health organizations involved in data analysis, healthcare policy & research (e.g. CDC)
• Education providers (e.g. simulation learning centers)
• Insurance companies
• Biotech firms
• Colleges & universities (e.g. teaching and/or research)

Some entrepreneurial types even develop their own healthcare IT businesses.

Note: Want two straightforward ways to define the scope of practice? Have a look at the Test Content Outline of the ANCC’s Informatics Nursing (NI-BC) exam under the section on ANCC Study Aids and the job responsibilities listed in HIMSS’s Nursing Informatics (NI) Workforce Survey.

Nursing Informatics Fields

The words “nursing informatics” encompass all kinds of healthcare-related disciplines. Here are some of the major duties associated with each field:

• Clinical Informatics: Employ your clinical RN experience and knowledge of IT solutions & data to serve medical providers in patient-based settings (e.g. hospitals, clinics & private practices).
• Consumer Health Informatics: Design, build, and improve telemedicine systems that promote better health, monitor patients, and administer care.
• Educational Health Informatics: Collaborate with faculty to invent web-based courses, online learning communities & simulation scenarios and integrate technology into clinical courses.
• Public Health Informatics: Use community & population health data to develop innovative programs (e.g. public health information networks, biosurvelliance programs, immunization registries, etc.) and supply policymakers with research-based advice.
• Research Informatics: Attain a doctoral degree to focus on a specific field of applied informatics research (e.g. impact of IT on health practices & outcomes; effectiveness of data communication technologies; methods of decision support for nurses; etc.).

We should point out that clinical informatics is the most popular field for nurses. Funding is now tied to patient outcomes, and many hospitals need to prove their worth through data.

• In 2023, almost two-thirds of Nursing Informatics (NI) Workforce Survey respondents worked at a hospital or a multi-facility health system.
• Over 6-in-10 worked in health systems with at least one hospital designated with Magnet Status.

But keep your mind open as you head into your studies. Certain fields like telemedicine are expanding rapidly as technology matures.

Why Pursue a Nursing Informatics Degree?

Benefits of a Nursing Informatics MSN

First things first: You may not need an MSN to become a nurse informaticist—most job positions list the BSN as the minimum baseline requirement. To improve their chances of hire, folks with a BSN sometimes earn a graduate certificate in nursing informatics instead of the more expensive graduate degree.

But since you’re on this site, we’re assuming you don’t have a BSN! If that’s the case, the RN to MSN Nursing Informatics program is going to be your most efficient option. It’s accelerated, it’s flexible, and it may help you earn a bachelor’s degree along the way. Other benefits of MSN program include:

• Advanced Nursing Knowledge: Most MSN programs in nursing informatics have a core of advanced practice subjects (e.g. nursing leadership, policy, evidence-based practice, regulatory issues, quality improvement & safety, etc.). This kind of interdisciplinary knowledge is critical when you’re tackling complex healthcare problems. You’re not locked into an “IT bubble.”
• Career-Specific Training: The right MSN program will include concentration courses in your specific area of interest (e.g. consumer health informatics). Better yet, you’ll be encouraged to apply your training to a practicum project under the supervision of a preceptor. You gain relevant work experience and networking contacts.
• Long-Term Prestige: An MSN is often the first step on the road to major leadership positions. If you’re aspiring to an IT-related management position (e.g. CIO, CNIO, Clinical Informatics Architect, etc.), a master’s degree is a qualification worth having.

Talk to your mentors, chat with alumni, and check out the duties listed in current job descriptions before you make a decision about pursuing a master’s degree in nursing informatics. If you do opt for the MSN, you’ll find there’s a lot of market demand for your skills.

Note: Nursing informatics programs do not lead to APRN state licensure. If you’re interested in graduate training for a specific clinical field (e.g. NP specialties, CNM, CNS), see the other specialty degree directories on this site.

RN to MSN Nursing Informatics Programs

RN to MSN Nursing Informatics: Overview

RN to MSN Nursing Informatics programs are designed for RNs who have a diploma or an associate’s degree (e.g. ASN/ADN) and want to pursue an MSN or MS. There are also RN to MSN Nursing Informatics programs for RNs who have a bachelor’s degree in a field other than nursing.

There are two types of nursing informatics master’s programs in our directory:

• RN to MSN in Nursing Informatics: An informatics program that includes a general advanced practice core and a number of concentration courses in informatics fields. This is the most common academic offering.
• RN to MSN in Nursing Leadership: Concentration in Nursing Informatics: A leadership-focused program with a concentration or track in nursing informatics. The coursework may slant toward topics such as leadership development, innovative change, and healthcare management.

Before you make a final decision, take some time to dig into the curricula. Because leadership & nursing informatics degrees deal with indirect patient care, they often have similar core coursework. You may find there’s no real difference between certain programs!

RN to MSN Nursing Informatics: Admissions

RN to MSN Nursing Informatics programs share the same general prerequisites as many other RN to MSN advanced nursing programs that deal with indirect patient care (e.g. RN to MSN Nursing Administration Programs and RN to MSN/MBA Programs). You’ll typically need to have:

• A diploma or associate’s degree in nursing (e.g. ADN or ASN) or a bachelor’s degree in another field from a regionally accredited institution
• A current RN license
• At least one year of full-time RN clinical experience
• A baseline undergraduate GPA (usually 2.75-3.0)—some schools will also ask for GMAT or GRE scores, especially if your GPA is not very high
• Letters of professional/academic reference

You can improve your chances of admission by demonstrating your expertise & enthusiasm for healthcare technologies. Check out our section on nursing informatics careers for ideas.

RN to MSN Nursing Informatics: Undergraduate Phase

Before you can start work on the MSN, you’ll be required to earn good grades on upper-level undergraduate courses through your chosen college or university.

The length of this phase will depend on what qualification you currently hold (e.g. ASN vs. non-nursing bachelor’s degree), but most coursework takes 6 months-2 years to complete.

Examples of prerequisite undergraduate courses can include:

• Conceptual bases of professional nursing practice
• Concepts & theories in nursing
• Nursing research & evidence-based practice
• Nursing leadership & management
• Community health nursing

Schools of Nursing almost always list statistics & health assessment as standard prerequisites for the MSN. Schools are usually willing to accept transfer credits or a health assessment portfolio for these two courses.

RN to MSN Nursing Informatics: MSN Curriculum

After you’ve finished your undergraduate courses, you can start to tackle the MSN. Every School of Nursing has their own unique take on informatics, but a number of universities now try to align their curricula with informatics competencies laid out by HIMSS.

For example, a sample curriculum might include:

• Core Courses: ~6-8 courses in advanced practice subjects (e.g. leadership; evidence-based practice; health policy & politics; advanced nursing research; ethics & law; etc.).
• Concentration Courses: ~3-6 courses in informatics (e.g. administrative informatics; healthcare database systems; IT project management; data management in healthcare; managing the nursing informatics life cycle; human-technology interactions in healthcare; etc.).

Informatics concentration courses vary widely between schools, so please check the curriculum to make sure you’re acquiring the skills you need. Some programs have a true technical feel; others are primarily focused on administrative & management issues. You can also look to see who’s teaching the courses (i.e. nursing faculty or IT experts).

In addition to traditional classroom work, almost all MSN nursing informatics programs include a capstone or scholarly project and practicums.

Note: We’ve spotted one or two RN to MSN programs that include the 3 fundamental courses of clinical practice—advanced pharmacology, advanced pathophysiology, and advanced health assessment—but they are rare.

RN to MSN Nursing Informatics: MSN Clinical Hours / Practicums

A lot of MSN programs in informatics try to include at least 200 faculty-supervised practicum hours in the graduate curriculum. That’s the minimum practice hour requirement for folks who have completed a graduate program in informatics nursing and wish to apply for ANCC’s NI-BC certification.

For instance, in your practicum you might be expected to design an informatics project that incorporates current theory & research, implement the project, and evaluate its success. Examples of nursing informatics practicums for MSN programs include:

• Implementation projects for new systems
• Process improvement projects
• Enhancement projects for current healthcare technology systems
• New performance measures
• Quality improvement department goals
• Workflow mapping
• Specification gathering
• Project presentations to end users or leadership

Common nursing informatics practicum sites include hospitals, clinic informatics departments, quality improvement departments, county health departments, EHR vendors, private providers’ offices, insurance companies, and the like.

Students are usually expected to arrange their own sites & preceptors, but talk to the program coordinator about your options. Some universities (especially ones in metro areas) have close ties with major hospitals and healthcare systems. These institutions often desperately need IT help.

Online RN to MSN Nursing Informatics Programs

Are Online RN to MSN Nursing Informatics Programs Available?

Yes. In fact, because this is a tech-heavy specialty that deals with indirect patient care, the majority of listings in our directory are Online RN to MSN Nursing Informatics programs. And even the on-campus ones are usually hybrid.

Here’s how a typical RN to MSN distance learning program is structured:

• Undergraduate Phase: Just like an on-campus degree, you’ll be required to earn good grades in upper-level undergraduate courses from the university. These courses are almost always offered online, so you can work while you study.
• Graduate Phase: You’ll be able to take all (or almost all) of your standard MS or MSN courses online. You can fulfill your practicums in your home community, but—as we mentioned—you may be expected to find the preceptor and arrange the setting. You’ll also have to pay for transit costs to the site.

Occasionally, a School of Nursing will ask you to visit the campus for a beginning orientation or a weekend residency, but a number of nursing informatics programs omit this aspect altogether.

Online RN to MSN Nursing Informatics Programs & State Authorization

Online RN to MSN Nursing Informatics programs are not designed to lead to advance practice state licensure. That means many of the regulations involving distance learning and clinical practicums disappear. In other words, you should be eligible for a number of online programs, regardless of your state of residence.

On the other hand, because of interstate agreements, Schools of Nursing may still be unable to accept certain out-of-state MSN applicants. You can usually find details about these issues on program websites or the school’s State Authorization or State Regulation page.

State authorization rules change frequently, so it’s always best to check with the program coordinator for clarification.

Nurse Informatics Certification

Overview of Nursing Informatics Certification

The standard certification for nursing informatics specialists is the Nursing Informatics – Board Certified (NI-BC™) qualification from the American Nurses Credentialing Center (ANCC). Until late 2023, this certification was called the Registered Nurse–Board Certified (RN-BC). So you may still see that acronym listed on various websites.

You can qualify for the NI-BC in a number of ways (e.g. extensive work experience), but you’ll notice that the ANCC is happy to accept candidates with a graduate degree in informatics nursing and 200 hours of faculty-supervised practicums. So make sure your MSN degree contains that magic number. Many RN to MSN Nurse Informatics programs will make a point of preparing you for ANCC certification.

The other common certification is the Certified Professional in Healthcare Information and Management Systems (CPHIMS®) from the Healthcare Information and Management Systems Society (HIMSS). This is a credential for more experienced professionals who have a few years of informatics work under their belt.

Leaders in the field might have both credentials. For example:

• Devon Ray RN, BSN, NI-BC, CPHIMS, Director of Nursing Informatics
• Penelope Garcia RN, MSN, NI-BC, CPHIMS, Clinical Informatics Architect
• Eileen Hubble DNP, NI-BC, NEA-BC, CPHIMS, FHIMSS, Vice President of Clinical Informatics

Note: FHIMSS stands for HIMSS’s Fellow in Healthcare Information & Management Systems.

Nursing Informatics Certifications

Nursing Informatics – Board Certified (NI-BC™)

The NI-BC certification is a specialty credential offered by the American Nurses Credentialing Center (ANCC). It demonstrates that you have entry-level clinical knowledge and skills in nursing informatics. To gain it, you must:

• Hold a current, active RN license.
• Hold a bachelor’s or higher degree in nursing.
• Have the equivalent of 2 years full-time work experience as an RN.
• Have completed 30 hours of continuing education in informatics nursing within the last 3 years.
• Have fulfilled one of the following criteria:
  • Have practiced a minimum of 2,000 hours in informatics nursing within the last 3 years
  • Have practiced a minimum of 1,000 hours in informatics nursing in the last 3 years + completed a minimum of 12 semester hours of academic credit in informatics courses that are part of a graduate-level informatics nursing program
  • Have completed a graduate program in informatics nursing with a minimum of 200 hours of faculty-supervised practicums in informatics nursing.

Once you have met these requirements, you must take & pass the Informatics Nursing Board Certification (BC) exam. This is a computer-based exam with 150 questions (125 scored + 25 pretest questions that are not scored). The 3 major categories are: Foundations of Practice; System Design Life Cycle; and Data Management & Healthcare Technology.

You can keep your NI-BC certification up-to-date through continuing education. Certification is valid for 5 years.

Healthcare Informatics Certifications

Certified Associate in Healthcare Information and Management Systems (CAHIMS®)

CAHIMS is offered by the Healthcare Information and Management Systems Society (HIMSS). It’s aimed at emerging professionals who may or may not have experience within the industry. To gain it, you must:

• Have a high school diploma (or the equivalent).
• Have at least 45 hours of continuing education in healthcare information technology, digital health or informatics, specifically covering content found on the CAHIMS Outline of Exam Topics or 150 hours experience in any type of IT and Healthcare setting or role (e.g. volunteer, practicum/internship, work).

OR

• Hold an associate, bachelor, or advanced degree from an accredited college or university.
• Have at least 25 hours of continuing education in healthcare information technology, digital health or informatics, specifically covering content found on the CAHIMS Outline of Exam Topics or 75 hours experience in any type of IT and Healthcare setting or role (e.g. volunteer, practicum/internship, work).

Once you have met these requirements, you must take & pass the CAHIMS exam. It’s a 2-hour exam with 115 multiple-choice questions, 100 of which are scored. The exam covers 4 major content areas: Healthcare and Technology Environments; Clinical Informatics; Healthcare Information and Systems Management; and Management Leadership.

You can keep your CAHIMS certification up-to-date through continuing education or successful re-examination. Certification is valid for 3 years.

Certified Professional in Healthcare Information and Management Systems (CPHIMS®)

CPHIMS is offered by the Healthcare Information and Management Systems Society (HIMSS). It’s a credential for experienced healthcare information and management systems professionals. To gain it, you must:

• Earn an accredited bachelor’s degree.
• Have 5 years of information & management systems experience (3 of those years in a healthcare setting)

OR

• Earn an accredited graduate degree or higher.
• Have 3 years of information & management systems experience (2 of those years in a healthcare setting).

OR

• Have at least 10 years of information and management systems experience (8 of those years in a healthcare setting).

Once you have met those requirements, you must take & pass the CPHIMS exam. It’s a 2-hour exam with 115 multiple-choice questions, 100 of which are scored. The exam covers 4 major content areas: Healthcare and Technology Environments; Clinical Informatics; Healthcare Information and Systems Management; and Management Leadership.

You can keep your CPHIMS certification up-to-date through continuing education or successful re-examination. Certification is valid for 3 years.

Nursing Informatics Jobs

Nursing Informatics Careers

A graduate degree in nursing informatics may help you win an interview, but you will need clinical and IT experience to secure a job. Employers will choose an RN with a BSN and significant IT skills over an RN with an MSN and little experience every time!

To buff up the IT portion of your résumé, you may wish to:

• Become a Super-User: Super-users are clinical care providers who have additional training on a specific technology (e.g. EHR system). With that knowledge in hand, they can then provide IT teaching & support to their colleagues (e.g. during a go-live/implementation phase). A lot of informatics professionals enter the field as super-users.
• Earn CAHIMS Certification: This is a “starter” qualification in health management & information systems offered by HIMSS. You only need a high school diploma to apply. We outline the exam procedure in our section on nursing informatics certifications.
• Join or Start an Informatics Committee: As one nurse pointed out, these have lots of different names, so you may need to ask around. Being on a committee/taskforce will give you inside knowledge of the field, as well as some of the real-world challenges involved in clinical information systems.
• Volunteer for IT-Related Projects: Ask the IT Department if you can road-test new healthcare technologies, software & programs. Offer to build IT solutions and online tools for your colleagues. Become the liaison person for vendor organizations & software companies.
• Write for Informatics Publications: Submit white papers, articles, and opinion pieces to healthcare journals and newsletters. You can start with the Journal of Informatics Nursing (JIN), but remember that publications in your specific field (e.g. pediatrics) will also be interested in IT perspectives.
• Train in Epic & Consider Epic Certification: Because Epic is one of the largest EHR systems on the market, it’s helpful to have some exposure to it. When it comes to Epic certification, you can become certified in a variety of Epic modules (e.g. Willow, Cupid, Stork, etc.). However, a) your employer must sponsor you; b) your employer must be an Epic customer/contractor; and c) you will need to travel to Epic headquarters in Wisconsin for training.
• Choose the Right MSN Practicum: Make sure your 200-hour practicum is focused on real-world projects with career applications. Some schools like to boast that their nursing students are hired as informaticians while they are still in the program—ask about your school’s employment rates at practicum sites.
• Network: Attend nursing informatics conferences & workshops. Contact informatics professionals through LinkedIn and ask them about their work experiences. Talk to program alumni about the job hunting process.

If you’re eyeing work in a hospital or healthcare system, employers will also be looking for relevant clinical expertise. In the 2023 Nursing Informatics (NI) Workforce Survey, over 25% of respondents had 6-10 years of clinical experience.

Nursing Informatics Job Openings

• Indeed: Nurse Informatics Jobs; Informatics Nurse Specialist Jobs.
• Monster: Nursing Informatics Jobs.
• Glassdoor: Nursing Informatics Jobs; Nurse Informatics Specialist Jobs.
• LinkedIn: Nursing Informatics Jobs.

Mid-Level Job Titles

• Informatics Nurse
• Informatics Coordinator
• Nursing Informatics Analyst
• Nurse Informaticist
• Nurse Informatics Specialist
• Informatics Nurse Specialist
• Quality Improvement Specialist
• IT Nursing Advocate
• Systems Analyst
• Clinical Data Analyst
• Clinical Informatics Expert
• Systems Administrator
• Clinical Informatics Manager
• IT Training Manager
• Project Manager

Note: According to the ANA’s Nursing Informatics: Scope and Standards of Practice, RNs who enter the informatics field via on-the-job training or continuing education courses are called “Informatics Nurses.” RNs with a formal graduate education in informatics are called “Informatics Nurse Specialists.”

High-Level Job Titles

• Director of Nursing Informatics
• Director of EHR Support
• Clinical Informatics Architect
• Chief Information Officer (CIO)
• Chief Nursing Informatics Officer (CNIO)
• Chief Medical Information Officer (CMIO)
• Vice President of Informatics

Nursing Informatics Salaries

The Bureau of Labor Statistics posts job data on medical records and health information technicians, but these stats usually only cover low-level positions. Your better bet is HIMSS’s salary reports, which are published regularly. In 2022, 60% of respondents reported an annual salary over $100,000.

You can get ballpark figures for most positions by looking at Payscale’s page on Nursing Informatics Salaries. This has a list of common informatics titles and their accompanying salaries. For example, in 2025:

• Informatics Nurses had an average annual salary of $87,000+.
• Clinical Informatics Specialists had an average annual salary of $90,000+.
• Nursing Informatics Specialists had an average annual salary of $91,000+.
• Clinical Informatics Managers had an average annual salary of $107,000+.
• Nursing Informatics Managers had an average annual salary of $107,500+.

Nursing Informatics Resources

Nursing Informatics Certification Bodies

• American Nurses Credentialing Center (ANCC)
• ANIA Certification Review Course for ANCC’s Informatics Nursing Certification
• Healthcare Information and Management Systems Society (HIMSS)

Nursing Informatics Professional Associations

• Alliance for Nursing Informatics (ANI)
• American Medical Informatics Association (AMIA)
• American Nurses Association (ANA)
• American Nursing Informatics Association (ANIA)
• Healthcare Information and Management Systems Society (HIMSS)
• International Medical Informatics Association (IMIA)
• New England Nursing Informatics Consortium (NENIC)

Nursing Informatics Conferences & Events

• AMIA Annual Symposium
• AMIA Clinical Informatics Conference
• AMIA Informatics Summit
• ANIA Annual Conference
• HIMSS Global Health Conference
• International Conference on Nursing Informatics
• Summer Institute in Nursing Informatics (SINI)

Nursing Informatics Journals

• Health Informatics Journal (JHI)
• International Journal of Medical Informatics (IJMI)
• Journal of the American Medical Informatics Association (JAMIA)
• Journal of Biomedical Informatics (JBI)
• Journal of Informatics Nursing (JIN)

Nursing Informatics Useful Resources

• AMIA Career Center
• AMIA Nursing Informatics Working Group
• ANA Nursing Informatics: Scope and Standards of Practice
• HIMSS JobMine
• HIMSS Resource Center
• HIMSS Scholarships
• HIMSS Nursing Informatics (NI) Workforce Survey
• Women in AMIA Initiative